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E-Cadherin antibody [67A4]

Cat No. GTX00607

Host

Mouse

Clonality

Monoclonal

Clone Name

67A4

Isotype

IgG1

Application

WB, ICC/IF, IHC-Fr, FACS, IP

Reactivity

Human
Package
100 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

97 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

T-47D cells

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Arc1,CD324,CDH1,CDHE,ECAD,LCAM,UVO,cadherin 1,E-Cadherin,Cadherin 1

Cellular Localization

Cell junction,Cell membrane,Endosome,Golgi apparatus,trans-Golgi network

Background

This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]

Database

Research Area

REFERENCE

There are currently no references for E-Cadherin antibody [67A4] (GTX00607). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for E-Cadherin antibody [67A4] (GTX00607). Be the first to share your experience with this product.
Package List Price ($)
$ 319