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Factor XIIIa antibody [F13A1/1448]

Anti-Factor XIIIa antibody [F13A1/1448] used in Western Blot (WB). GTX34714
Anti-Factor XIIIa antibody [F13A1/1448] used in IHC (Paraffin sections) (IHC-P). GTX34714

Cat No. GTX34714

Host Mouse
Clonality Monoclonal
Clone Name F13A1/1448
Isotype IgG2b
Application WB, ICC/IF, IHC-P
Reactivity Human
100 μg ($429)

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5-1.0ug/ml
ICC/IF 0.5-1ug/ml
IHC-P 1-2ug/ml for 30 minutes at RT

Note :

Boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes

Not tested in other applications.

Calculated MW

83 kDa. ( Note )


It recognizes a protein of 83kDa, which is identified as Factor XIIIa. It has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-factor XIIIa has been found to be useful in differentiating between dermatofibroma (almost all cases are positive), dermatofibrosarcoma protuberans (-/+) and desmoplastic malignant melanoma (-). Anti-factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor, and meningioma.




10mM PBS with 0.05% BSA, 0.05% azide (Please contact us for PBS only format)


Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.


0.2 mg/ml

Antigen Species



Recombinant fragment of human Factor XIIIa protein (aa46-181) (exact sequence is proprietary)


Ab purified from Bioreactor Concentrate by Protein A/G




For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.


Coagulation Factor Xiii A Chain , F13A , F13A1


This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. [provided by RefSeq, Jul 2008]


Research Area

Anti-Factor XIIIa antibody [F13A1/1448] used in Western Blot (WB). GTX34714

GTX34714 WB Image

Western Blot Analysis of Recombinant Protein and HeLa Cell Lysate using Factor XIIIa Monoclonal Antibody (F13A1/1448).

Anti-Factor XIIIa antibody [F13A1/1448] used in IHC (Paraffin sections) (IHC-P). GTX34714

GTX34714 IHC-P Image

Formalin-fixed, paraffin-embedded human Histiocytoma stained with Factor XIIIa Monoclonal Antibody (F13A1/1448).

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