*Optimal dilutions/concentrations should be determined by the researcher.
Heat induced antigen retrieval in pH 6.0 citrate buffer
Not tested in other applications.
Chicken, Elephant, Gibbon, Gorilla, Marmoset, Opossum, Panda, Xenopus, Platypus(>80% identity)
PBS, 0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Synthetic 18 amino acid peptide from C-terminus of human FZD7 / Frizzled 7.
Purified by affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
frizzled class receptor 7 , FZD7 , FzE3
Cell membrane,Endosome membrane
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]
GTX12996 IHC-P Image
IHC-P analysis of human heart tissue using GTX12996 Frizzled 7 antibody.
Antigen retrieval : Heat-induced antigen retrieval