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GABA B Receptor 1 antibody

Anti-GABA B Receptor 1 antibody used in Western Blot (WB). GTX30215

Cat No. GTX30215

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
Package
100 μl ($329)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500
Not tested in other applications.

Calculated MW

108 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS, 0.02% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to residues 33-54 [PHLPRPHPRVPPHPSSERRAVY] of the GABABR1 subunit.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

gamma-aminobutyric acid type B receptor subunit 1 , GABABR1 , GABBR1-3 , GB1 , GPRC3A

Cellular Localization

Cell membrane,Cell projection, dendrite

Background

Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates 4 transcript variants. [provided by RefSeq]

Database

Research Area

DATA IMAGES
Anti-GABA B Receptor 1 antibody used in Western Blot (WB). GTX30215

GTX30215 WB Image

WB analysis of brain tissue lysate using GTX30215 GABA B Receptor 1 antibody.
Dilution : 1:500

REFERENCE
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REVIEW
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Package List Price ($)
$ 329