10 mM Sodium Citrate, pH 3.5.
Reconstitute to a concentration of 0.1-1.0 mg/ml in water containing BSA (50 mg BSA per 1 mg of protein). This solution can then be diluted into other aqueous buffers. Stored at -20ºC for future use.
Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
GDF5, Growth differentiation factor 5, CDMP1, Radotermin, Growth differentiation factor5, Cartilage-derived morphogenetic protein-1, LAP4, CDMP-1, Cartilagederived morphogenetic protein1, GDF-5, BMP-14, BMP14, SYNS2, GDF 5, CDMP 1, BMP 14
BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. In addition to its osteogenic activity, BMP-14 is a principal inhibitor of cartilage development and is predominantly expressed in long bone during human embryonic development. Recombinant human BMP-14 is a 27 kDa homodimeric protein consisting of two 120 amino acid polypeptide chains.