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GLE1 antibody

Anti-GLE1 antibody used in Western Blot (WB). GTX31366
Anti-GLE1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31366
Anti-GLE1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31366

Cat. No. GTX31366

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all GLE1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

80 kDa. ( Note )

Positive Control

Mouse Brain Tissue Lysate(GTX27934)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Gle1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human Gle1.The immunogen is located within amino acids 540 - 590 of Gle1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

GLE1 RNA export mediator , CAAHC , CAAHD , GLE1L , LCCS , LCCS1 , hGLE1

Cellular Localization

Nucleus,Cytoplasm

Background

This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-GLE1 antibody used in Western Blot (WB). GTX31366

GTX31366 WB Image

WB analysis of mouse brain tissue lysate using GTX31366 GLE1 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Anti-GLE1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31366

GTX31366 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX31366 GLE1 antibody.
Working concentration : 2.5 μg/ml

Anti-GLE1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31366

GTX31366 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX31366 GLE1 antibody.
Working concentration : 5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399