APPLICATION
Product Note
The peptide was used in the production of GTX88922.
PROPERTIES
Form
Lyophilized powder
Buffer
Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O.
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Region/Sequence
C-ERDPDKQTQNKE
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
Set Domain Containing 2 , Hbp231 , Hif-1 , Hip-1 , Hspc069 , Hypb , Kmt3A , Lls , Set2 , P231Hbp , Setd2
Background
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
Research Area
REFERENCE
There are currently no references for HYPB/SETD2 (internal region) blocking peptide (GTX88922-PEP). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for HYPB/SETD2 (internal region) blocking peptide (GTX88922-PEP). Be the first to share your experience with this product.