APPLICATION
Application Note
ELISA: Use at an assay dependent dilution. WB: Use at a concentration of 0.5 μg/ml. Detects Recombinant ChimericHCV Polyprotein at a band of approximately 60 kDa (predicted molecular weight: 60 kDa). Optimal dilutions/concentrations should be determined by the end user.
Product Note
GTX19052 reacts with synthetic NS4a Protein (1689a.a.-1735a.a.) and recombinant Chimeric HCV Polyprotein (60 kDa). No cross reaction with synthetic recombinant Capsid Protein C + Envelope Protein M (core)(1a.a.-142a.a.), synthetic Capsid Protein C (1a.a.-61a.a.), recombinant NS3 Protein (1252a.a.-1477a.a.) and synthetic NS3 Protein (1378a.a.-1458a.a.)
PROPERTIES
Form
Liquid
Buffer
0.01M PBS pH7.0
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Hepatitis C virus
Immunogen
Recombinant full length protein (Purified recombinant Chimeric HCV Polyprotein, 555aa)
Purification
Immunogen affinity purified
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
Hepatitis C Virus Non-structural protein 4A , Hepatitis C Virus NS4A , HCV Non-structural protein 4A , HCV NS4A
Cellular Localization
RNA virus
Background
HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non-structural protein necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.
Research Area
DATA IMAGES
![Anti-Hepatitis C virus NS4A protein antibody [497] used in Western Blot (WB). GTX19052](/templates/default/js/lightbox/images/loading.gif "Anti-Hepatitis C virus NS4A protein antibody [497] used in Western Blot (WB). GTX19052")
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GTX19052 WB Image
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REFERENCE
There are currently no references for Hepatitis C virus NS4A protein antibody [497] (GTX19052). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Hepatitis C virus NS4A protein antibody [497] (GTX19052). Be the first to share your experience with this product.
![Anti-Hepatitis C virus NS4A protein antibody [497] used in Western Blot (WB). GTX19052](/upload/website/prouct_img/small/GTX19052/Hepatitis-C-NS4-antibody-497-GTX19052-WB-1_18121411_265.jpg "Anti-Hepatitis C virus NS4A protein antibody [497] used in Western Blot (WB). GTX19052")
![Anti-Hepatitis C virus NS4A protein antibody [497] used in Western Blot (WB). GTX19052](/upload/website/prouct_img/normal/GTX19052/Hepatitis-C-NS4-antibody-497-GTX19052-WB-1_18121411_265.jpg "Anti-Hepatitis C virus NS4A protein antibody [497] used in Western Blot (WB). GTX19052")