Human FGF2 protein (active)

Cat. No. GTX01349-pro

Application	Functional Assay
Species	Human
Package	100 μg ($279)

See all FGF2 protein products

Datasheet

APPLICATION

Application Note

Measured in a cell proliferation assay using Balb/c 3T3 cells. The ED₅₀ for this effect is typically 0.02-0.1 ng/ml.

Observed MW

16.5 kDa.

PROPERTIES

Form

Lyophilized powder

Buffer

Batch dependent (please contact us for details)

Storage

Store at -20ºC or below. After reconstitution, keep as concentrated solution. Avoid freeze-thaw cycles.

Region/Sequence

No tagged; Pro143-Ser288 of Human FGF2 protein (NP_001997.5)

Expression System

E. coli

Purity

> 95% by SDS-PAGE.

Endotoxin

< 1.0 EU/μg (determined by LAL method)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BFGF,FGF-2,FGFB,HBGF-2

Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008]

Database

Gene ID: 2247 FGF2
UniProt: P09038 FGF2

Research Area

DATA IMAGES

GTX01349-pro Functional Assay Image

The protein activity of GTX01349-pro Human FGF2 protein was measured in a cell proliferation assay using Balb/c 3T3 cells.
ED₅₀ : 0.02-0.1 ng/ml

GTX01349-pro Image

SDS-PAGE of 5 μg GTX01349-pro Human FGF2 protein (active).

REFERENCE

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Package

List Price ($)

100 μg

$ 279

Qty