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Human ICAM1 (ECD) protein, His tag (active)

Human ICAM1 (ECD) protein, His tag (active). GTX03489-pro

Cat. No. GTX03489-pro

Species

Human
Package
50 μg ($399)

APPLICATION

Application Note

Measured by the ability of the immobilized protein to support the adhesion of PMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemia cells. When cells are added to ICAM1-coated plates (12.5 μg/ml, 100 μl/well), approximately 30%-60% will adhere specifically.

Observed MW

65-70 kDa.

PROPERTIES

Form

Lyophilized powder

Buffer

Batch dependent (please contact us for details)

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Region/Sequence

C-terminal polyhistidine tag; human ICAM1 (NP_000192.2) extracellular domain (Met 1-Glu 480)

Expression System

HEK293 Cells

Purity

>98 % by SDS-PAGE

Endotoxin

<1.0EU/1μg (determined by the LAL method)

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

intercellular adhesion molecule 1 , BB2 , CD54 , P3.58

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Human ICAM1 (ECD) protein, His tag (active). GTX03489-pro

GTX03489-pro Image

SDS-PAGE of GTX03489-pro Human ICAM1 (ECD) protein, His tag (active).

REFERENCE

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REVIEW

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Package List Price ($)
$ 399