GeneTex
United States (US)

I-309 protein

Cat No. GTX29854

Reactivity Human
Species Human
APPLICATION

Positive Control

Recombinant hIL-11 (ab
PROPERTIES

Form

Lyophilized powder

Storage

The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20 ºC. We recommend a quick spin followed by reconstitution in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other buffer

Antigen Species

Human

Immunogen

Highly pure (>98%) recombinant hIL-11 (human Interleukin-11)

Region/Sequence

Highly pure (>98%) recombinant hIL-11 (human Interleukin-11)

Purification


Sterile filtered Greater than 98% pure by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

C-C Motif Chemokine Ligand 1,I-309,P500,Scya1,Sise,Tca3,Ccl1

Cellular Localization

Secreted

Background

I-309 is a member of the C-C, or beta chemokine class. Other chemokines in this group include MIP1 alpha, MIP1 beta, RANTES, MCP1/2/3/4, mouse JE, 1 - 2 μg/ml antibody detects 20 and mouse MARC, eotaxin, HCC1 and C10. These chemokines act primarily as chemoattractants and activate monocytes, dendritic cells, T lymphocytes, natural killer cells, B lymphocytes, basophils and eosinophils. I-309 was originally identified by subtractive hybridization as a transcript that was present in a gamma/delta T cell line but not in EBVtransformed B cells. I-309 is a chemoattractant for monocytes, but not for neutrophils. IP-10 is an approximately 8.5 kD polypeptide of 73 amino acids. The precursor form of human I-309 consists of 96 amino acids. To generate the mature I-309, the precursor cleaves its hydrophobic signal peptide. Human I-309 is thought to be a homologue of the mouse TCA3, and shows 42% amino acid homology to mouse TCA3.
Package List Price ($)
$ 299