GeneTex
United States (US)

IL27 recombinant protein

Cat No. GTX65467

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Mouse
Species Mouse
APPLICATION

Application Note

Measured by dose-dependent inhibition of TGF-beta & Il-6-induced IL-17A expression in mouse CD4 splenocytes. 50 ng/ml of mouse p28 is capable of inhibiting ≥25% of Il-17A expression in this assay.

Calculated MW

23.7 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Buffer

10 mM NaP, pH 7.5

Storage

Reconstitute in water to a concentration of 0.1-1.0 μg/μl. The solution can then be diluted into other aqueous buffers. Stored at -20ºC for future use.

Antigen Species

Mouse

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥97%) and by HPLC (≥97%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Interleukin27/p28, Interleukin27 subunit alpha, Interleukin30, Interleukin-2, Il27, Interleukin27, IL-27, p28, IL27 subunit alpha, IL30, Interleukin-30, Interleukin-27/p28, Interleukin2, IL-30, Interleukin-27, IL27p28., IL-27 subunit alpha, Il27a, IL 27, IL 30, Interleukin 2, Interleukin 30, Interleukin 27, Interleukin 27/p28, IL 27 subunit alpha

Background

Recombinant mouse IL-27/p28 Subunit, also known as Interleukin-30, is a member of the IL-12 family of Cytokines. When combined with EBI3 (Epstein-Barr virus induced gene 3), the heterodimer formed is IL-27. Mouse p28 is a proinflammatory cytokine inducing immunomodulatory effects. Current research is underway to delineate specific biological functions. Recombinant mouse p28 is a single-chain 207 amino acid peptide with a mass of approximately 23.7 kDa.

Research Area

Package List Price ($)
$ 319