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IL31 antibody

Anti-IL31 antibody used in Western Blot (WB). GTX85642
Anti-IL31 antibody used in IHC (Paraffin sections) (IHC-P). GTX85642
Anti-IL31 antibody used in IHC (Paraffin sections) (IHC-P). GTX85642

Cat. No. GTX85642

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human
Package
50 μg ($569)
See all IL31 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P 5 μg/ml
ELISA Assay dependent
Not tested in other applications.

Calculated MW

18 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A 18 amino acid synthetic peptide near the center of human IL-31. The immunogen is located within amino acids 60 - 110 of IL-31.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_10722558

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interleukin 31 , IL31

Cellular Localization

Secreted

Background

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008]

Database

Research Area

DATA IMAGES

Anti-IL31 antibody used in Western Blot (WB). GTX85642

GTX85642 WB Image

WB analysis of human skeletal muscle tissue lysate using GTX85642 IL31 antibody.
Dilution : 2.5 μg/mL (Lane A), 5 μg/mL (Lane B), and 10 μg/mL (Lane C)

Anti-IL31 antibody used in IHC (Paraffin sections) (IHC-P). GTX85642

GTX85642 IHC-P Image

IHC-P analysis of human skeletal muscle tissue using GTX85642 IL31 antibody.
Dilution : 20 μg/ml

Anti-IL31 antibody used in IHC (Paraffin sections) (IHC-P). GTX85642

GTX85642 IHC-P Image

IHC-P analysis of human thymus tissue using GTX85642 IL31 antibody.
Antigen retrieval : Heat-induced antigen retrieval
Dilution : 5 μg/ml

REFERENCE

Application Reference

Patra V et al. Br J Dermatol 2019; (Epub) CD11b+ cells markedly express the itch cytokine interleukin 31 in polymorphic light eruption.
Application : IHC-P
Reactivity : Human
Submit a Reference

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 569