GeneTex
United States (US)

IL32A (Active) recombinant protein

Cat No. GTX65300

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

Human IL-32 alpha activity is measured via the dose-dependent induction of TNF-alpha in the human THP-1 monocytic cell line.

Calculated MW

14.9 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Buffer

50 mM NaP, pH 7.5.

Storage

It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions. Stored at -20ºC for future use.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥97%) and by HPLC.

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

IL32a, IL-32alpha, IL32, IL-32beta, Tumor necrosis factor alpha inducing factor, IL32delta, Interleukin32, IL32alpha, Interleukin32 alpha ., Interleukin-32 alpha ., Interleukin-32, IL-32delta, IL32gamma, Tumor necrosis factor alpha -inducing factor, IL32beta, IL 32beta, IL 32alpha, IL 32delta, Interleukin 32, Interleukin 32 alpha .

Background

Human IL-32 alpha is one of approximately 6 splice variants of a gene cloned from the human lung carcinoma stable transfectant, A549-Rbeta. IL-32 alpha has been shown to induce IL-8, TNF-alpha , and MIP-2 production from human & 22 macrophage cell lines. It is up-regulated in activated T- & NK-cells, and IFN-g-treated epithelial cells. Human recombinant IL-32 alpha produced in E. coli is a 131 amino acid non-glycosylated polypeptide with a molecular mass of 14.9 kDa.

Research Area

Package List Price ($)
$ 299