Integrin alpha 4 antibody [R1-2] (PerCP-Cy5.5)

Cat. No. GTX01513-11
References 2
Cat. No.  GTX01513-11
Anti-Integrin alpha 4 antibody [R1-2] (PerCP-Cy5.5) used in Flow cytometry (FCM). GTX01513-11
GTX01513-11 FCM Image

FACS analysis of mouse C57Bl/6 splenocytes using GTX01513-11 Integrin alpha 4 antibody [R1-2] (PerCP-Cy5.5).
Solid lone : primary antibody
Dashed line : isotype control
antibody amount : 0.25 μg (5 μl)

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Anti-Integrin alpha 4 antibody [R1-2] (PerCP-Cy5.5) used in Flow cytometry (FCM). GTX01513-11
  • Host
    Rat
  • Clonality
    Monoclonal
  • Clone Name
    R1-2
  • Isotype
    IgG2b
  • Applications
    FCM
  • Reactivity
    Mouse
Summary
The R1-2 monoclonal antibody reacts with mouse CD49d, a 150kD glycoprotein member of the integrin αfamily. CD49d is also known as integrin αalpha4 (ITGA4). Together with integrin αbeta1 (CD29), CD49d forms the VLA-4 heterodimer that serves as a receptor for fibronectin and VCAM-1. VLA-4 is widely expressed on lymphocytes, monocytes, thymocytes, and NK cells. CD49d can dimerize with integrin αbeta7 to form a receptor that binds the mucosal vascular addressin molecule, MAdCAM-1.
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