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Integrin beta 4 antibody [10B10D5]

Anti-Integrin beta 4 antibody [10B10D5] used in ELISA (ELISA). GTX60736
Anti-Integrin beta 4 antibody [10B10D5] used in Flow cytometry (FACS). GTX60736
Anti-Integrin beta 4 antibody [10B10D5] used in IHC (Paraffin sections) (IHC-P). GTX60736
Anti-Integrin beta 4 antibody [10B10D5] used in IHC (Paraffin sections) (IHC-P). GTX60736
Anti-Integrin beta 4 antibody [10B10D5] used in Western Blot (WB). GTX60736

Cat. No. GTX60736

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 10B10D5

Isotype

 IgG1

Application

 WB, IHC-P, FACS, ELISA

Reactivity

 Human
Package
100 μl ($409)
See all Integrin beta 4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
IHC-P 1/200 - 1/1000
FACS 1/200 - 1/400
ELISA 1/10000
Not tested in other applications.

Calculated MW

202 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human ITGB4 (AA: 1619-1822) expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit beta 4 , CD104 , GP150

Cellular Localization

Cell membrane; Single-pass type I membrane protein

Background

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Integrin beta 4 antibody [10B10D5] used in ELISA (ELISA). GTX60736

GTX60736 ELISA Image

ELISA analysis of antigen using GTX60736 Integrin beta 4 antibody [10B10D5].
Black : Control antigen 100ng
Purple : Antigen 10ng
Blue : Antigen 50ng
Red : Antigen 100ng

Anti-Integrin beta 4 antibody [10B10D5] used in Flow cytometry (FACS). GTX60736

GTX60736 FACS Image

FACS analysis of A549 cells using GTX60736 Integrin beta 4 antibody [10B10D5].
Green : Integrin beta 4
Purple : negative control

Anti-Integrin beta 4 antibody [10B10D5] used in IHC (Paraffin sections) (IHC-P). GTX60736

GTX60736 IHC-P Image

IHC-P analysis of cervical cancer tissue using GTX60736 Integrin beta 4 antibody [10B10D5].

Anti-Integrin beta 4 antibody [10B10D5] used in IHC (Paraffin sections) (IHC-P). GTX60736

GTX60736 IHC-P Image

IHC-P analysis of esophageal cancer tissue using GTX60736 Integrin beta 4 antibody [10B10D5].

Anti-Integrin beta 4 antibody [10B10D5] used in Western Blot (WB). GTX60736

GTX60736 WB Image

WB analysis of A549 (1), A431 (2), MCF-7 (3) and SW620 (4) cell lysate using GTX60736 Integrin beta 4 antibody [10B10D5].

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 409