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Leptin antibody [11] (Biotin)

Anti-Leptin antibody [11] (Biotin) used in ELISA (ELISA). GTX60983-02

Cat. No. GTX60983-02

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 11

Isotype

 IgG1

Application

 ELISA

Reactivity

 Human
Package
50 μl ($599)
See all Leptin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ELISA Assay dependent
Not tested in other applications.

Calculated MW

19 kDa. ( Note )

Product Note

This antibody binds human leptin.

PROPERTIES

Form

Liquid

Buffer

0.01M Phosphate buffer pH7.4, 0.14M NaCl

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human leptin

Purification

Biotinylated

Conjugation

Biotin

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

leptin , LEPD , OB , OBS

Cellular Localization

Secreted

Background

This gene encodes a protein that is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in the brain, which activates downstream signaling pathways that inhibit feeding and promote energy expenditure. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis, reproduction, bone formation and wound healing. Mutations in this gene and its regulatory regions cause severe obesity and morbid obesity with hypogonadism in human patients. A mutation in this gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-Leptin antibody [11] (Biotin) used in ELISA (ELISA). GTX60983-02

GTX60983-02 ELISA Image

The calibration curve of a sandwich assay for Leptin using GTX60964 as the capture antibody and GTX60983-02 as the biotinylated detection antibody.

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 599