United States (US)

Leptin recombinant protein

Cat No. GTX65157

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human

Application Note

GeneTex' s human Leptin has been shown to be biologically active in two different mouse obesity models, ob/ob and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 mg Leptin/gm of body weight for 7 days. Significant effects on body weight, food consumption, and plasma glucose levels were observed to saline-treated controls.

Calculated MW

16.0 kDa. ( Note )


Lyophilized powder


Add 15 mM sterile HCl (0.5 ml/1 mg vial or 5 ml/10 mg vial) to the vial. After the protein is completely dissolved, add 7.5 mM sterile NaOH (0.3 ml/1 mg vial or 3 ml/10 mg vial) to bring the pH to approximately 5.2. Stored at -20ºC for future use.

Antigen Species


Expression System

E. coli


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).


For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.


Obesity Protein, OBS, OB Protein, Obesity factor., LEP


Leptin (Anti-Obesity Protein) is the protein product of the ob (obese) gene in mice and seems to be involved in appetite control. The ob gene is expressed in adipose tissue and is thought to regulate the body’s fat stores. Mice with the ob/ob genotype also develop a form of diabetes similar to type II (non-insulin dependent) diabetes. Human Leptin is a 16 kDa protein containing 146 amino acid residues.

Research Area

Package List Price ($)
$ 199