APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| Assay dependent |
| Assay dependent |
| Assay dependent |
Not tested in other applications.
Calculated MW
Product Note
This antibody reacts with NGAL (neutrophil gelatinase-associated lipocalin) from Macaca mulatta (Rhesus) and Macaca facicularis (Cynomolgus)
PROPERTIES
Form
Liquid
Buffer
0.01M Phosphate buffer, 0.5M NaCl
Preservative
15mM Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant monkey NGAL
Purification
Protein-A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
lipocalin 2 , 24p3 , MSFI , NGAL , p25
Cellular Localization
Secreted
Background
This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. [provided by RefSeq, Sep 2015]
Database
Research Area
DATA IMAGES
![Anti-Lipocalin-2 antibody [56] used in ELISA (ELISA). GTX60968](/templates/default/js/lightbox/images/loading.gif "Anti-Lipocalin-2 antibody [56] used in ELISA (ELISA). GTX60968")
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GTX60968 ELISA Image
The calibration curve of a sandwich assay for Monkey NGAL using GTX60968 as the capture antibody and GTX60987-02 as the biotinylated detection antibody.
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GTX60968 IHC Image
IHC staining for nephrotoxicant-induced NGAL protein expression in male Cynomolgus monkey using the BioPorto Diagnostics antibody (GTX60968) at 1:50. Mild multifocal staining was localized in apical surface of intact tubular epithelial cells in the cortex and medulla (left panel) and marked multifocal tubular cast (granular and cellular) in the cortex (right panel). Image: Kindly provided by McDuffie, J.E., J.Y. Ma et al (Janssen Research & Development, L.L.C.)
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REFERENCE
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REVIEW
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![Anti-Lipocalin-2 antibody [56] used in ELISA (ELISA). GTX60968](/upload/website/prouct_img/small/GTX60968/GTX60968_20170208_ELISA_w_23061202_789.webp "Anti-Lipocalin-2 antibody [56] used in ELISA (ELISA). GTX60968")
![Anti-Lipocalin-2 antibody [56] used in Immunohistochemistry (IHC). GTX60968](/upload/website/prouct_img/small/GTX60968/GTX60968_20170208_IHC_w_23061202_645.webp "Anti-Lipocalin-2 antibody [56] used in Immunohistochemistry (IHC). GTX60968")
![Anti-Lipocalin-2 antibody [56] used in ELISA (ELISA). GTX60968](/upload/website/prouct_img/normal/GTX60968/GTX60968_20170208_ELISA_w_23061202_789.webp "Anti-Lipocalin-2 antibody [56] used in ELISA (ELISA). GTX60968")
![Anti-Lipocalin-2 antibody [56] used in Immunohistochemistry (IHC). GTX60968](/upload/website/prouct_img/normal/GTX60968/GTX60968_20170208_IHC_w_23061202_645.webp "Anti-Lipocalin-2 antibody [56] used in Immunohistochemistry (IHC). GTX60968")