For FACS, IA, IHC-Fr and WB: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.
Reacts specificly with human 180 kDa mannose receptor
PBS, 0.1% BSA
0.02% Sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
0.1 mg/ml (Please refer to the vial label for the specific concentration.)
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
mannose receptor C-type 1 , CD206 , CLEC13D , CLEC13DL , MMR , MRC1L1 , bA541I19.1 , hMR
Endosome membrane , Cell membrane
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]