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Mannose Receptor antibody [15-2] (Biotin)

Cat. No. GTX28919

Reference 3

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 15-2

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P, IHC-Fr, FACS, Immunoassay

Reactivity

 Human, Mouse, Rat
Package
250 μl ($409)
See all Mannose Receptor products

APPLICATION

Application Note

For FACS, IA, IHC-Fr and WB: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

166 kDa. ( Note )

Product Note

Reacts specificly with human 180 kDa mannose receptor

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Purification

IgG fraction

Conjugation

Biotin

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

mannose receptor C-type 1 , CD206 , CLEC13D , CLEC13DL , MMR , MRC1L1 , bA541I19.1 , hMR

Cellular Localization

Endosome membrane , Cell membrane

Background

The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]

Database

Research Area

REFERENCE

Clone Reference

GH Han et al. Cell Prolif 2021; 54:e13050 Transplantation of tauroursodeoxycholic acid-inducing M2-phenotype macrophages promotes an anti-neuroinflammatory effect and functional recovery after spinal cord injury in rats
Application : ICC/IF, IHC-P, FACS
Reactivity : Rat
GK Katara et al. Oncogene 2014; 33 (49):5649-54 Tumor-associated vacuolar ATPase subunit promotes tumorigenic characteristics in macrophages
Application : ICC/IF
Reactivity : Human
PA Walker et al. J Neuroinflammation 2012; 9:228 Intravenous multipotent adult progenitor cell therapy after traumatic brain injury: modulation of the resident microglia population
Application : ICC/IF
Reactivity : Mouse
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 409