Mre11 antibody [12D7]

Cat. No. GTX70212
Cat. No.  GTX70212
Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

Non-transfected (–) and transfected (+) HeLa whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Mre11 antibody [12D7] (GTX70212) diluted at 1:500. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

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Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membranes were blotted with Mre11 antibody [12D7] (GTX70212) diluted at 1:1000 and competitor's antibody diluted at 1:500. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

*The competitor is not affiliated with GeneTex and does not endorse this product.

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Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membranes were blotted with Mre11 antibody [12D7] (GTX70212) diluted at 1:1000 and competitor's antibody diluted at 1:1000. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

*The competitor is not affiliated with GeneTex and does not endorse this product.

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Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
GTX70212 ICC/IF Image

Mre11 antibody [12D7] detects Mre11 protein at nucleus by immunofluorescent analysis.
Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: Mre11 stained by Mre11 antibody [12D7] (GTX70212) diluted at 1:200.
Blue: Hoechst 33342 staining.
Scale bar= 10 μm.

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Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with Mre11 antibody [12D7] (GTX70212) diluted at 1:500. The HRP-conjugated anti-mouset IgG antibody (GTX213111-01) was used to detect the primary antibody.

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Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

Mre11 antibody [12D7] detects Mre11 protein by western blot analysis.
A. 30 μg 293T whole cell extract
B. 30 μg whole cell extract of human Mre11-transfected 293T cells
7.5% SDS-PAGE
Mre11 antibody [12D7] (GTX70212) dilution: 1:1000
The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody.

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Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
GTX70212 ICC/IF Image

The data was published in the journal Viruses in 2015.PMID: 26057167

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Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
GTX70212 ICC/IF Image

The data was published in the journal J Virol in 2017.PMID: 28855246

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Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
GTX70212 ICC/IF Image

The data was published in the journal PLoS Pathog in 2010.PMID: 20949077

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Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
GTX70212 ICC/IF Image

The data was published in the journal Nucleic Acids Res in 2016. PMID: 26446986

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Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
GTX70212 ICC/IF Image

The data was published in the journal Nucleic Acids Res in 2016. PMID: 26446986

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Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

The data was published in the journal BMC Biol in 2015. PMID: 25857663

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Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

The data was published in the journal Nat Commun in 2017.PMID: 29042561

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Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

The data was published in the journal Open Biol in 2015.PMID: 25924630

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Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

The data was published in the journal PLoS One in 2015.PMID: 25826455

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Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

The data was published in the journal BMC Cancer in 2014.PMID: 24928521

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Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
GTX70212 ICC/IF Image

The data was published in the journal Open Biol in 2015.PMID: 25924630

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Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
GTX70212 WB Image

The data was published in the journal Nat Commun in 2017.PMID: 29042561

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Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
Anti-Mre11 antibody [12D7] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70212
Anti-Mre11 antibody [12D7] used in Western Blot (WB). GTX70212
  • Host
    Mouse
  • Clonality
    Monoclonal
  • Clone Name
    12D7
  • Isotype
    IgG1
  • Applications
    WB ICC/IF IP ELISA Functional Assay PLA
  • Reactivity
    Human
Summary
MRE11 antibody recognizes MRE11 protein, an enzyme with a predicted molecular weight of ~81 kDa. MRE11 forms the core of the MRN (MRE11-RAD50-NBS1) complex, one of the first components of the DNA damage response (DDR) to DNA double-strand breaks where it recruits other signaling factors required for repair. MRE11 has both exonuclease and endonuclease activities, and is responsible for the DNA binding of the complex.
See all Mre11 products