Preservative: 0.05% Sodium Azide; Constituents: Whole Serum
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Synthetic peptide: NHQLENLEAETAPLP, corresponding to C terminal amino acids 384-398 of Rat Mu Opioid Receptor.
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Oprm1, MORA, 25601, Mu Opioid receptor
Integral membrane protein.
The powerful effects of opiate are mediated through the opioid receptors located on the plasma membrane of neurons and other peripheral cells. There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile. The mu opioid receptor is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. Three types of opioid receptors have been cloned mu, delta, and kappa. Opioid receptors are seven transmembrane G-protein coupled receptors. They share a high degree of homology and are most divergent at the N and C-termini. Activation of mu opioid receptors leads to a decrease in neuronal excitability. Expression of Mu Opioid Receptor has been reported mostly in brain and spinal cord.