APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
4 - 22 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Rat, Rabbit, Chimpanzee, Elephant, Gibbon, Gorilla, Horse, Marmoset, Opossum, Panda, Platypus(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 18 amino acid peptide from C-terminus of human OPRM1 / Mu Opioid Receptor.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
opioid receptor mu 1 , LMOR , MOP , MOR , MOR1 , OPRM , OPRM1 , Mu Opioid receptor
Cellular Localization
Cell membrane,Cell projection,Axon,Perikaryon,Dendrite,Endosome,Cytoplasm
Background
This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. [provided by RefSeq, Oct 2013]
Database
Research Area
DATA IMAGES
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GTX13074 IHC-P Image
IHC-P analysis of brain, putamen tissue using GTX13074 Mu Opioid receptor antibody.
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GTX13074 IHC-P Image
IHC-P analysis of human brain, glioblastoma tissue using GTX13074 Mu Opioid receptor antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX13074 IHC-P Image
IHC-P analysis of human brain, neuron tissue using GTX13074 Mu Opioid receptor antibody. Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
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REVIEW
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