APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1 - 2 μg/mL |
| Assay dependent |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Jurkat Cell Slide(GTX25533) , Jurkat Cell Lysate(GTX27899) , Human Lymph node Tissue Lysate(GTX29055)
Product Note
At least four isoforms of NOD2 are known to exist; this antibody will only detect the longest isoform. NOD2 has no cross-reaction with NOD1.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
NOD2 antibody was raised against a synthetic peptide corresponding to 16 amino acids at the amino terminus of human NOD2.The immunogen is located within the first 50 amino acids of NOD2.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
nucleotide binding oligomerization domain containing 2 , ACUG , BLAU , BLAUS , CARD15 , CD , CLR16.3 , IBD1 , NLRC2 , NOD2B , PSORAS1 , YAOS
Cellular Localization
Cytoplasm,Membrane,Mitochondrion
Background
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX31664 WB Image
WB analysis of human lymph node tissue lysate using GTX31664 NOD2 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml
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GTX31664 ICC/IF Image
ICC/IF analysis of Jurkat cells using GTX31664 NOD2 antibody.
Working concentration : 5 μg/ml
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GTX31664 ICC/IF Image
ICC/IF analysis of Jurkat cells using GTX31664 NOD2 antibody.
Working concentration : 20 μg/ml
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REFERENCE
There are currently no references for NOD2 antibody (GTX31664). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for NOD2 antibody (GTX31664). Be the first to share your experience with this product.
