NSE antibody [N1C1]
Cat. No. GTX101553
Cat. No. GTX101553
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HostRabbit
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ClonalityPolyclonal
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IsotypeIgG
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ApplicationsWB IHC-P IHC-Fr
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ReactivityHuman, Mouse, Rat
Summary
NSE is a 78 kDa gamma-homodimer expressed as a dominant enolase-isoenzyme in neuronal and neuroendocrine tissues. Elevated levels of serum NSE are often associated with neuronal disorders and neural crest-derived tumors. Up to 70 percent of patients with small cell lung carcinoma (SCLC) have high levels of serum NSE, as SCLC cells can express neuronal gene programs.