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Neurofibromin antibody

Anti-Neurofibromin antibody used in Western Blot (WB). GTX66693

Cat No. GTX66693

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB

Reactivity

Human, Mouse, Rat
Package
100 μl ($349)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:1000
Not tested in other applications.

Calculated MW

319 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.2, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide, corresponding to amino acids 1550-1600 of Human Neurofibromin.

Purification

Purified by antigen-affinity chromatography
From serum

Purity

> 95% (by SDS-PAGE)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

neurofibromin 1 , NFNS , VRNF , WSS

Cellular Localization

Nucleus,Nucleus, nucleolus

Background

This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Neurofibromin antibody used in Western Blot (WB). GTX66693

GTX66693 WB Image

WB analysis of various samples using GTX66693 Neurofibromin antibody.
Lane1 : MCF-7 whole cell lysate(40ug)
Lane2 : Panc1 whole cell lysate(40ug)
Lane3 : HEK293T whole cell lysate(40ug)
Lane4 : CT26 whole cell lysate(40ug)
Lane5 : H9C2 whole cell lysate(40ug)
Dilution : 1:500

REFERENCE

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REVIEW

There are currently no reviews for Neurofibromin antibody (GTX66693). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf