GeneTex
United States (US)

P2Y12 antibody

GTX16888_WB_18121410_382.jpg
GTX16888_FACS_18121410_651.jpg
GTX16888_ICCIF_18121410_115.jpg

Cat No. GTX16888

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, FACS
Reactivity Human, Rat
APPLICATION

Calculated MW

39 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Peptide CTAENTLFYVKES, corresponding to amino acid residues 270-282 of human P2Y12 receptor (Accession Q9H244). 3rd extracellular loop.

Purification

Affinity purified on immobilized antigen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Purinergic Receptor P2Y12,Adpg-R,Bdplt8,Hork3,P2T(Ac),P2Y(12)R,P2Y(Ac),P2Y(Adp),P2Y(Cyc),P2Y12,Sp1999,P2Ry12

Background

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX16888_WB_18121410_382.jpg

GTX16888 WB Image

Anti-P2Y12_Receptor_(extracellular) - Western blot analysis of rat brain membrane (lanes 1 and 3) and MEG-01 (lanes 2 and 4) cell line lysate: 1-2. Anti-P2Y12 Receptor (extracellular) antibody, (1:200). 3-4. Anti-P2Y12 Receptor (extracellular) antibody, preincubated with the control peptide antigen.

GTX16888_FACS_18121410_651.jpg

GTX16888 FACS Image

Anti-P2Y12_Receptor_(extracellular) - Indirect flow cytometry analysis of MEG-O1 living cells: ___ Unstained cells.___ Cells + Anti-P2Y12 Receptor (extracellular) antibody, (5-10 μg/1x106 cells).

GTX16888_ICCIF_18121410_115.jpg

GTX16888 ICC/IF Image

Anti-P2Y12_Receptor_(extracellular) - Expression of P2Y12 in rat RBL cells Immunocytochemical staining of intact living rat basophilic leukemia (RBL) cells. A. Extracellular staining of cells using Anti-P2Y12 (extracellular) antibody, (1:100) followed by goat anti-rabbit-AlexaFluor-594 secondary antibody (red). B. Live view of the cells.

Package List Price ($)
$ 329