Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Peptide CTAENTLFYVKES, corresponding to amino acid residues 270-282 of human P2Y12 receptor (Accession Q9H244). 3rd extracellular loop.
Affinity purified on immobilized antigen.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purinergic Receptor P2Y12,Adpg-R,Bdplt8,Hork3,P2T(Ac),P2Y(12)R,P2Y(Ac),P2Y(Adp),P2Y(Cyc),P2Y12,Sp1999,P2Ry12
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene. [provided by RefSeq, Jul 2008]