APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Dilution |
| Assay dependent |
| Assay dependent |
| Assay dependent |
| Assay dependent |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS pH7.4, 1% BSA
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.8 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Peptide CTAENTLFYVKES, corresponding to amino acid residues 270-282 (3rd extracellular loop) of human P2RY12 (Accession : Q9H244).
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
purinergic receptor P2Y12 , ADPG-R , BDPLT8 , HORK3 , P2T(AC) , P2Y(12)R , P2Y(AC) , P2Y(ADP) , P2Y(cyc) , P2Y12 , SP1999
Cellular Localization
Cell membrane
Background
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Database
Research Area
DATA IMAGES
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GTX16888 FACS Image
FACS analysis of MEG-O1 cells using GTX16888 P2Y12 antibody.
Black : Unstained cell
Green : Cell staining with primary antibody
Antibody amount : 5-10 μg antibody / 1 x 10⁶ cells
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GTX16888 WB Image
WB analysis of rat brain membrane (lanes 1 and 3) and MEG-01 (lanes 2 and 4) lysates using GTX16888 P2Y12 antibody preincubated with or without immunogen peptide.
Dilution : 1:200
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GTX16888 LCI Image
Live cell imaging analysis of intact living RBL cells using GTX16888 P2Y12 antibody.
Panel A : Primary antibody
Panel B : Live view of the cell
Dilution : 1:100
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REFERENCE
There are currently no references for P2Y12 antibody (GTX16888). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for P2Y12 antibody (GTX16888). Be the first to share your experience with this product.
