P2Y12 antibody

Cat. No. GTX16888

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF, FACS, LCI
Reactivity	Human, Rat
Package	50 μl ($639)

See all P2Y12 products

Datasheet
Document

View product citations for antibody GTX16888 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	Assay dependent
ICC/IF	Assay dependent
FACS	Assay dependent
LCI	Assay dependent

Not tested in other applications.

Calculated MW

39 kDa. ( Note )

Predict Reactivity

Mouse(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.8 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide CTAENTLFYVKES, corresponding to amino acid residues 270-282 (3rd extracellular loop) of human P2RY12 (Accession : Q9H244).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

purinergic receptor P2Y12 , ADPG-R , BDPLT8 , HORK3 , P2T(AC) , P2Y(12)R , P2Y(AC) , P2Y(ADP) , P2Y(cyc) , P2Y12 , SP1999

Cellular Localization

Cell membrane

Background

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

Database

Gene ID: 64805 P2RY12
UniProt: Q9H244 P2RY12

Research Area

DATA IMAGES

GTX16888 FACS Image

FACS analysis of MEG-O1 cells using GTX16888 P2Y12 antibody.
Black : Unstained cell
Green : Cell staining with primary antibody
Antibody amount : 5-10 μg antibody / 1 x 10⁶ cells

GTX16888 WB Image

WB analysis of rat brain membrane (lanes 1 and 3) and MEG-01 (lanes 2 and 4) lysates using GTX16888 P2Y12 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

GTX16888 LCI Image

Live cell imaging analysis of intact living RBL cells using GTX16888 P2Y12 antibody.
Panel A : Primary antibody
Panel B : Live view of the cell
Dilution : 1:100

REFERENCE

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SDS
PBS.pdf
Sodium Azide.pdf

Package

List Price ($)

50 μl

$ 639

Qty