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PAI-1 antibody

Anti-PAI-1 antibody used in Western Blot (WB). GTX79739

Cat No. GTX79739

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, IHC-Fr, ELISA

Reactivity

Human
Package
500 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

45 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.05M Sodium Phosphate pH 6.6, 0.1M NaCl, 1mM EDTA

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

10 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full length wild-type human protein (Non-glycosylated).

Purification

Protein A purified
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

PAI,PAI1,PLANH1,SERPINE1,serpin family E member 1,PAI-1,Serpin E1

Cellular Localization

Secreted

Background

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Database

Research Area

DATA IMAGES

Anti-PAI-1 antibody used in Western Blot (WB). GTX79739

GTX79739 WB Image

WB analysis of various sample lysates using GTX79739 PAI-1 antibody.
Lane 1 : Human PAI-I (0.5 μg) Reduced
Lane 2 : Human PAI-1 (0.5 μg) + Human uPA (2.0 μg) Reduced
Lane 3 : Molecular Weight Markers

REFERENCE

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REVIEW

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Package List Price ($)
$ 319