GeneTex
United States (US)

PCNA antibody [131-11964(19F4)]

Cat No. GTX39739

Host Mouse
Clonality Monoclonal
Clone Name 131-11964(19F4)
Isotype IgG1
Reactivity Human
APPLICATION

Calculated MW

29 kDa. ( Note )

Specificity/Sensitivity

PCNA (Proliferating Cell Nuclear Antigen), formerly called Cyclin, is a 36 kDa proliferation associatedantigen.
PROPERTIES

Form

Liquid

Buffer

10 mM Phosphate pH 7.4, 150 mM sodium chloride, 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.20 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified Proliferating Cell Nuclear Antigen

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Proliferating Cell Nuclear Antigen,Atld2,Pcna

Background

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]

Database

Research Area

Package List Price ($)
$ 319