GeneTex

  • Country / Location Selection

United States (US)

PGCB antibody

Anti-PGCB antibody used in Western Blot (WB). GTX14784
Anti-PGCB antibody used in Immunohistochemistry (IHC). GTX14784

Cat. No. GTX14784

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IP, ELISA, IHC

Reactivity

 Human, Mouse, Rat
Package
100 μg ($409)
See all PGCB products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500
ICC/IF 1:200
IP 1:200
ELISA 1:10000
IHC 1:200
Not tested in other applications.

Calculated MW

117 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tris/Glycine, 0.5% BSA, 30% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.75-1.20 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase B protein.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

natriuretic peptide receptor 2 , AMDM , ANPRB , ANPb , ECDM , GUC2B , GUCY2B , NPRB , NPRBi , SNSK

Cellular Localization

Cell membrane

Background

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-PGCB antibody used in Western Blot (WB). GTX14784

GTX14784 WB Image

WB analysis of PGCB recombinant protein using GTX14784 PGCB antibody.
Dilution : 1:500

Anti-PGCB antibody used in Immunohistochemistry (IHC). GTX14784

GTX14784 IHC Image

IHC analysis of mouse nose tissue using GTX14784 PGCB antibody. Staining is found on blood vessel walls.
Red : Primary antibody
Green : Greneberg ganglion nerons
Staining is found on blood vessel walls.

REFERENCE

There are currently no references for PGCB antibody (GTX14784). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for PGCB antibody (GTX14784). Be the first to share your experience with this product.
Submit a Review
Package List Price ($)
$ 409