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PPAR gamma antibody

Cat No. GTX19481

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat, Bovine, Dog, Hamster, Chicken, Pig
Package
200 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:400
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

Product Note

React with PPARgamma1 and PPARgamma2.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1 % sodium azide, 0.2% gelatin

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide mapping near the carboxy terminus of human PPARgamma.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_425200

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

peroxisome proliferator activated receptor gamma , CIMT1 , GLM1 , NR1C3 , PPARG1 , PPARG2 , PPARgamma

Cellular Localization

Nucleus , Cytoplasm

Background

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

REVIEW

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