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PRMT6 antibody [2C3-F1-G1]

Anti-PRMT6 antibody [2C3-F1-G1] used in IHC (Paraffin sections) (IHC-P). GTX49197
Anti-PRMT6 antibody [2C3-F1-G1] used in Western Blot (WB). GTX49197
Anti-PRMT6 antibody [2C3-F1-G1] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX49197

Cat No. GTX49197

Host

Mouse

Clonality

Monoclonal

Clone Name

2C3-F1-G1

Isotype

IgG1

Application

WB, ICC/IF, IHC-P

Reactivity

Human
Package
100 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

42 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant human PRMT6 protein fragments expressed in E.coli.

Purification

Affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Protein Arginine Methyltransferase 6 , Hrmt1L6 , Prmt6

Cellular Localization

Nucleus

Background

PRMT6 is a protein arginine N-methyltransferase, and catalyzes the sequential transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation is a prevalent post-translational modification in eukaryotic cells that has been implicated in signal transduction, the metabolism of nascent pre-RNA, and the transcriptional activation processes. IPRMT6 is functionally distinct from two previously characterized type I enzymes, PRMT1 and PRMT4. In addition, PRMT6 displays automethylation activity; it is the first PRMT to do so. PRMT6 has been shown to act as a restriction factor for HIV replication.

Database

Research Area

DATA IMAGES

Anti-PRMT6 antibody [2C3-F1-G1] used in IHC (Paraffin sections) (IHC-P). GTX49197

GTX49197 IHC-P Image

IHC-P analysis of human breast cancer using PRMT6 antibody at a dilution of 1:200.

Anti-PRMT6 antibody [2C3-F1-G1] used in Western Blot (WB). GTX49197

GTX49197 WB Image

WB analysis of HeLa and 293T lysates using PRMT6 antibody at a dilution of 1:1,000.

Anti-PRMT6 antibody [2C3-F1-G1] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX49197

GTX49197 ICC/IF Image

ICC/IF analysis of HeLa cells using PRMT6 antibody at a dilution of 1:300.

REFERENCE

There are currently no references for PRMT6 antibody [2C3-F1-G1] (GTX49197). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for PRMT6 antibody [2C3-F1-G1] (GTX49197). Be the first to share your experience with this product.
SDS
Glycerol.pdf
Sodium Azide.pdf