GeneTex

  • Country / Location Selection

United States (US)

PRMT6 antibody [2C3-F1-G1]

Anti-PRMT6 antibody [2C3-F1-G1] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX49197
Anti-PRMT6 antibody [2C3-F1-G1] used in Western Blot (WB). GTX49197
Anti-PRMT6 antibody [2C3-F1-G1] used in IHC (Paraffin sections) (IHC-P). GTX49197

Cat. No. GTX49197

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 2C3-F1-G1

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all PRMT6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

42 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.5% BSA, 50% glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant human PRMT6 protein fragments expressed in E.coli.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

protein arginine methyltransferase 6 , HRMT1L6

Cellular Localization

Nucleus

Background

The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011]

Database

Research Area

DATA IMAGES

Anti-PRMT6 antibody [2C3-F1-G1] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX49197

GTX49197 ICC/IF Image

ICC/IF analysis of HeLa cells using PRMT6 antibody at a dilution of 1:300.

Anti-PRMT6 antibody [2C3-F1-G1] used in Western Blot (WB). GTX49197

GTX49197 WB Image

WB analysis of HeLa and 293T lysates using PRMT6 antibody at a dilution of 1:1,000.

Anti-PRMT6 antibody [2C3-F1-G1] used in IHC (Paraffin sections) (IHC-P). GTX49197

GTX49197 IHC-P Image

IHC-P analysis of human breast cancer using PRMT6 antibody at a dilution of 1:200.

REFERENCE

There are currently no references for PRMT6 antibody [2C3-F1-G1] (GTX49197). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for PRMT6 antibody [2C3-F1-G1] (GTX49197). Be the first to share your experience with this product.
Submit a Review
SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399