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PTGER4 / EP4 antibody

Overexpression
Anti-PTGER4 / EP4 antibody used in IHC (Paraffin sections) (IHC-P). GTX13379
Anti-PTGER4 / EP4 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX13379

Cat. No. GTX13379

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 ICC/IF, IHC-P

Reactivity

 Human
Package
25 μg ($299)
See all PTGER4 / EP4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-P 10 - 20 μg/ml
Not tested in other applications.

Calculated MW

53 kDa. ( Note )

Predict Reactivity

Monkey, Chimpanzee, Gibbon, Gorilla, Marmoset(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 14 amino acid peptide from N-terminal extracellular domain of human PTGER4 / EP4.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

prostaglandin E receptor 4 , EP4 , EP4R , PTGER4 , Prostaglandin E Receptor EP4

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-PTGER4 / EP4 antibody used in IHC (Paraffin sections) (IHC-P). GTX13379

GTX13379 IHC-P Image

IHC-P analysis of human colon, ganglion tissue using GTX13379 PTGER4 / EP4 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-PTGER4 / EP4 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX13379

GTX13379 ICC/IF Image

Overexpression

ICC/IF analysis of HEK293 transfected with PTGER4 / EP4 using GTX13379 PTGER4 / EP4 antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 299