Reconstitute in water to a concentration of 0.1-1 μg/μl. This solution can then be diluted into other aqueous buffers and stored at 4ºC for 1 week or –20ºc for future use.
Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Tcellspecific RANTES protein, MGC17164., TCP228, SISd, chemokine (C-C motif) ligand 5, SCYA5, chemokine (CC motif) ligand 5, T cell specific prot, CCL5, RANTES, T cell specific protein P228, D17S136E, SISdelta, T-cell-specific RANTES protein, T cell- specific prot, chemokine (CC motif) ligand5, T cell specific prot, chemokine (C C motif) ligand 5, T cell specific RANTES protein
RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.