GeneTex
United States (US)

RANTES recombinant protein

Cat No. GTX65238

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

Protein's bioactivity determined by its ability to chemoattract human blood monocytes using a concentration range of 1-10 ng/ml.

Calculated MW

7.8 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Storage

Reconstitute in water to a concentration of 0.1-1 μg/μl. This solution can then be diluted into other aqueous buffers and stored at 4ºC for 1 week or –20ºc for future use.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tcellspecific RANTES protein, MGC17164., TCP228, SISd, chemokine (C-C motif) ligand 5, SCYA5, chemokine (CC motif) ligand 5, T cell specific prot, CCL5, RANTES, T cell specific protein P228, D17S136E, SISdelta, T-cell-specific RANTES protein, T cell- specific prot, chemokine (CC motif) ligand5, T cell specific prot, chemokine (C C motif) ligand 5, T cell specific RANTES protein

Background

RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Research Area

Package List Price ($)
$ 249