GeneTex
United States (US)

ROR alpha antibody [N2N3]

KO/KD
GTX100029_39224_WB_M_Brain_19011505_387.jpg
GTX100029_WB_19011506_939.jpg
GTX100029_WB_M_19011506_970.jpg

Cat No. GTX100029

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

63 kDa. ( Note )

Positive Control

HeLa , HepG2 , Molt-4 , mouse brain , NIH-3T3

Predict Reactivity

Rat, Bovine, Xenopus tropicalis(>80% identity)
PROPERTIES

Form

Liquid

Buffer

1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ROR alpha. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

DKFZp686M2414 antibody, MGC119326 antibody, MGC119329 antibody, NR1F1 antibody, ROR1 antibody, ROR2 antibody, ROR3 antibody, RZR-ALPHA antibody, RZRA antibody, RORA antibody, nuclear receptor subfamily 1 group F member 1 antibody, retinoic acid receptor-related orphan receptor alpha antibody, transcription factor RZR-alpha antibody, nuclear receptor RZR-alpha antibody, retinoid-related orphan receptor alpha antibody, ROR-alpha antibody, thyroid hormone nuclear receptor alpha variant 4 antibody, nuclear receptor ROR-alpha antibody, RAR-related orphan receptor A antibody

Background

The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX100029_39224_WB_M_Brain_19011505_387.jpg

GTX100029 WB Image

Sample (50 ug of whole cell lysate)
A: Mouse brain
7.5% SDS PAGE
GTX100029 diluted at 1:1000

GTX100029_WB_19011506_939.jpg

GTX100029 WB Image

Sample (30 ug of whole cell lysate)
A: Hela
7.5% SDS PAGE
GTX100029 diluted at 1:1000

GTX100029_WB_M_19011506_970.jpg

GTX100029 WB Image

Sample (30 ug of whole cell lysate)

A:NIH-3T3
7.5% SDS PAGE

GTX100029 diluted at 1:5000

REFERENCE
SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Document
Unmodified.pdf