GeneTex
United States (US)

RPSA antibody

GTX31902_3048_WB_20180221_18121410_326.jpg
GTX31902_1556_IHC-P_20180221_18121410_697.jpg
GTX31902_1554_IHC-P_20180221_18121410_503.jpg
GTX31902_1553_IHC-P_20180221_18121410_630.jpg

Cat No. GTX31902

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

Positive Control

Caco-2 Cell Lysate(GTX23950)
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

RPSA antibody was raised against a 17 amino acid peptide near the carboxy terminus of human RPSA.The immunogen is located within amino acids 190 - 240 of RPSA.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Ribosomal Protein Sa,37Lrp,67Lr,Icas,Lambr,Lamr1,Lbp,Lbp/P40,Lrp,Lrp/Lr,Nem/1Chd4,Sa,Lamr,P40,Rpsa

Background

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX31902_3048_WB_20180221_18121410_326.jpg

GTX31902 WB Image

WB analysis of Caco-2 cell lysate using GTX31902 RPSA antibody.
Working concentration : 1 μg/ml

GTX31902_1556_IHC-P_20180221_18121410_697.jpg

GTX31902 IHC-P Image

IHC-P analysis of mouse liver tissue using GTX31902 RPSA antibody.
Working concentration : 20 μg/ml

GTX31902_1554_IHC-P_20180221_18121410_503.jpg

GTX31902 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX31902 RPSA antibody.
Working concentration : 20 μg/ml
Green : Primary antibody
Blue : DAPI
Red : Actin

GTX31902_1553_IHC-P_20180221_18121410_630.jpg

GTX31902 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX31902 RPSA antibody.
Working concentration : 5 μg/ml

Package List Price ($)
$ 329