SARM1 antibody [HL1066]
Cat. No. GTX636097
Cat. No. GTX636097
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HostRabbit
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ClonalityMonoclonal
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Clone NameHL1066
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IsotypeIgG
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ApplicationsWB ICC/IF IHC-P
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ReactivityHuman, Mouse, Rat
Summary
SARM1 antibody detects NAD(+) hydrolase SARM1, a key factor with a predicted molecular weight of ~79 kDa. SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration. SARM1 inhibition is being actively studied to prevent axonal degeneration associated with neurodegenerative disorders.