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SLC31A1 / CTR1 antibody

Anti-SLC31A1 / CTR1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30642
Anti-SLC31A1 / CTR1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30642
Anti-SLC31A1 / CTR1 antibody used in IHC (Paraffin sections) (IHC-P). GTX30642

Cat. No. GTX30642

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IHC-Fr

Reactivity

 Human, Mouse, Rat, Zebrafish, Pig, Xenopus
Package
100 μl ($419)
See all SLC31A1 / CTR1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF 1:500
IHC-P 1:250
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

21 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tris-Citrate/Phosphate

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide derived from a C-terminal sequence of human SLC31A1/CTR1 [UniProt# O15431]

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

solute carrier family 31 member 1 , COPT1 , CTR1

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, and intracellular compartmentalization or buffering of copper strictly regulated. The 2 related genes ATP7A (MIM 300011) and ATP7B (MIM 606882), responsible for the human diseases Menkes syndrome (MIM 309400) and Wilson disease (MIM 277900), respectively, are involved in copper export. In S. cerevisiae, the copper uptake genes CTR1, CTR2, and CTR3 have been identified, and in human the CTR1 and CTR2 (MIM 603088) genes have been identified.[supplied by OMIM]

Database

Research Area

DATA IMAGES

Anti-SLC31A1 / CTR1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30642

GTX30642 ICC/IF Image

ICC/IF analysis of NIH-3T3 cells using GTX30642 SLC31A1 / CTR1 antibody.
Green : primary antibody
Red : Tubulin
Blue : DAPI

Anti-SLC31A1 / CTR1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30642

GTX30642 ICC/IF Image

ICC/IF analysis of SLC31A1 / CTR1 overexpressing cells with (left) or without (right) peptide competition using GTX30642 SLC31A1 / CTR1 antibody.

Anti-SLC31A1 / CTR1 antibody used in IHC (Paraffin sections) (IHC-P). GTX30642

GTX30642 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX30642 SLC31A1 / CTR1 antibody.
Panel 1: human CTR1 staining of breast cancer tissue
Panel 2: human CTR1-antigen competition in breast cancer tissue

REFERENCE

Application Reference

Yang Wen et al. Anim Nutr 2022; 8 (1) : 321-330 Different copper sources and levels affect growth performance, copper content, carcass characteristics, intestinal microorganism and metabolism of finishing pigs.
Application : WB
Reactivity : Pig
Submit a Reference

REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 419