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SMN1 antibody [2F1]

Anti-SMN1 antibody [2F1] used in ELISA (ELISA). GTX60451
Anti-SMN1 antibody [2F1] used in IHC (Paraffin sections) (IHC-P). GTX60451
Anti-SMN1 antibody [2F1] used in Flow cytometry (FACS). GTX60451
Anti-SMN1 antibody [2F1] used in Western Blot (WB). GTX60451

Cat No. GTX60451

Host

Mouse

Clonality

Monoclonal

Clone Name

2F1

Isotype

IgG1

Application

WB, IHC-P, FACS, ELISA

Reactivity

Human, Monkey
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1/500 - 1/2000
IHC-P 1/200 - 1/1000
FACS 1/200 - 1/400
ELISA 1/10000
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites, 0.03% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human SMN1 expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

survival of motor neuron 1, telomeric , BCD541 , GEMIN1 , SMA , SMA1 , SMA2 , SMA3 , SMA4 , SMA@ , SMN , SMNT , T-BCD541 , TDRD16A

Cellular Localization

Cytoplasm

Background

This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein. However, mutations in this gene, the telomeric copy, are associated with spinal muscular atrophy; mutations in the centromeric copy do not lead to disease. The centromeric copy may be a modifier of disease caused by mutation in the telomeric copy. The critical sequence difference between the two genes is a single nucleotide in exon 7, which is thought to be an exon splice enhancer. Note that the nine exons of both the telomeric and centromeric copies are designated historically as exon 1, 2a, 2b, and 3-8. It is thought that gene conversion events may involve t

Database

Research Area

DATA IMAGES

Anti-SMN1 antibody [2F1] used in ELISA (ELISA). GTX60451

GTX60451 ELISA Image

ELISA analysis of antigen using GTX60451 SMN1 antibody [2F1].
Red : Control antigen 100ng
Purple : Antigen 10ng
Green : Antigen 50ng
Blue : Antigen 100ng

Anti-SMN1 antibody [2F1] used in IHC (Paraffin sections) (IHC-P). GTX60451

GTX60451 IHC-P Image

IHC-P analysis of testis tissue (left) and lung cancer tissue (right) using GTX60451 SMN1 antibody [2F1].

Anti-SMN1 antibody [2F1] used in Flow cytometry (FACS). GTX60451

GTX60451 FACS Image

FACS analysis of HepG2 cells using GTX60451 SMN1 antibody [2F1].
Green : SMN1
Purple : negative control

Anti-SMN1 antibody [2F1] used in Western Blot (WB). GTX60451

GTX60451 WB Image

WB analysis of HepG2 (1), HeLa (2), K562 (3), Jurkat (4), SKBR-3 (5), A431 (6) and Cos7 (7) cell lysate using GTX60451 SMN1 antibody [2F1].

REFERENCE

There are currently no references for SMN1 antibody [2F1] (GTX60451). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for SMN1 antibody [2F1] (GTX60451). Be the first to share your experience with this product.
SDS
Sodium Azide.pdf