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SOX10 antibody [SOX10/1074]

Anti-SOX10 antibody [SOX10/1074] used in IHC (Paraffin sections) (IHC-P). GTX35084
Anti-SOX10 antibody [SOX10/1074] used in Western Blot (WB). GTX35084
Anti-SOX10 antibody [SOX10/1074] used in Protein Array (Protein Array). GTX35084
Anti-SOX10 antibody [SOX10/1074] used in IHC (Paraffin sections) (IHC-P). GTX35084

Cat. No. GTX35084

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 SOX10/1074

Isotype

 IgG2b

Application

 WB, IHC-P, Protein Array

Reactivity

 Human, Mouse
Package
100 μg ($529)
See all SOX10 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2μg/ml
IHC-P 1-2μg/ml for 30 minutes at RT
Protein Array Assay dependent

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

Product Note

This MAb is highly specific and does not cross-react with other members of the SOX-family.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human SOX10 protein fragment (around aa115-269) (exact sequence is proprietary)

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

DOM , PCWH , SOX10 , SRYbox 10 , WS2E , WS4 , WS4C , SRY-box transcription factor 10

Cellular Localization

Cytoplasm,Nucleus,Mitochondrion outer membrane

Background

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-SOX10 antibody [SOX10/1074] used in IHC (Paraffin sections) (IHC-P). GTX35084

GTX35084 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX35084 SOX10 antibody [SOX10/1074].

Anti-SOX10 antibody [SOX10/1074] used in Western Blot (WB). GTX35084

GTX35084 WB Image

WB analysis of (A) SOX10 recombinant protein and (B) A375 cell lysates using GTX35084 SOX10 antibody [SOX10/1074].

Anti-SOX10 antibody [SOX10/1074] used in Protein Array (Protein Array). GTX35084

GTX35084 Protein Array Image

Analysis of Protein Array containing more than 19,000 full-length human proteins using SOX10 Mouse Monoclonal Antibody (SOX10/1074). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.

Anti-SOX10 antibody [SOX10/1074] used in IHC (Paraffin sections) (IHC-P). GTX35084

GTX35084 IHC-P Image

IHC-P analysis of human melanoma tissue using GTX35084 SOX10 antibody [SOX10/1074].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529