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STEP / PTPN5 antibody [23E5]

Anti-STEP / PTPN5 antibody [23E5] used in Western Blot (WB). GTX30465

Cat. No. GTX30465

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 23E5

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-Fr, IP, IHC

Reactivity

 Human, Mouse, Rat
Package
100 μl ($419)
See all STEP / PTPN5 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000 - 1:2000
ICC/IF 1:100 - 1:500
IHC-Fr 1:100 - 1:500
IP 1:50
IHC 1:100 - 1:500
Not tested in other applications.

Product Note

This antibody is specific for STEP61, STEP46, STEP38, and STEP20.

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Rat

Immunogen

A synthetic peptide of rat STEP46 (amino acids 57-74: MCTPGCNEEGFGYLVSPR)

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Background

Tyrosine phosphorylation plays a critical role in many physiological processes. There is a fine balance between phosphorylation caused by protein tyrosine kinases and actions of protein tyrosine phosphatases, that regulates these physiological processes. Striatal enriched phosphatase (STEP) is part of a family of protein tyrosine phosphatases enriched within the CNS and is a component of the NMDAR complex. It is expressed within dopaminoceptive neurons in the CNS and particularly enriched within the basal ganglia and related structures.

Research Area

DATA IMAGES

Anti-STEP / PTPN5 antibody [23E5] used in Western Blot (WB). GTX30465

GTX30465 WB Image

WB analysis of rat striatal protein homogenates using GTX30465 STEP antibody [23E5].

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 419