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Synaptotagmin 1 (phospho Thr202) + Synaptotagmin 2 (phospho Thr199) antibody

Anti-Synaptotagmin 1 (phospho Thr202) + Synaptotagmin 2 (phospho Thr199) antibody used in Western Blot (WB). GTX52318

Cat. No. GTX52318

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all Synaptotagmin 1 + Synaptotagmin 2 products

APPLICATION

Application Note

WB 1:500-1:2000, IHC 1:50-1:200

Calculated MW

48 kDa. ( Note )

Product Note

The sequence around Synaptotagmin 1 (phospho Thr202) is conserved with the sequence around Synaptotagmin 2 (phospho Thr199).SYT1

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human Synaptotagmin around the phosphorylation site of Thr202

Purification

Antigen affinity purification

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

synaptotagmin 1 , BAGOS , P65 , SVP65 , SYT

Cellular Localization

Cytoplasm

Background

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]).[supplied by OMIM, Jul 2010]

Database

Research Area

DATA IMAGES

Anti-Synaptotagmin 1 (phospho Thr202) + Synaptotagmin 2 (phospho Thr199) antibody used in Western Blot (WB). GTX52318

GTX52318 WB Image

Western blot analysis of Synaptotagmin phosphorylation expression in Forskolin treated 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

REFERENCE

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399