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TIE2 antibody

Anti-TIE2 antibody used in Western Blot (WB). GTX64389
Anti-TIE2 antibody used in IHC (Paraffin sections) (IHC-P). GTX64389
Anti-TIE2 antibody used in IHC (Paraffin sections) (IHC-P). GTX64389

Cat No. GTX64389

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

126 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 500-750 of human TEK (NP_000450.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

TEK receptor tyrosine kinase , CD202B , GLC3E , TIE-2 , TIE2 , VMCM , VMCM1

Cellular Localization

Cell membrane,Cell junction,Cytoplasm, cytoskeleton,Secreted

Background

This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]

Database

Research Area

DATA IMAGES

Anti-TIE2 antibody used in Western Blot (WB). GTX64389

GTX64389 WB Image

WB analysis of various sample lysates using GTX64389 TIE2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-TIE2 antibody used in IHC (Paraffin sections) (IHC-P). GTX64389

GTX64389 IHC-P Image

IHC-P analysis of human placenta tissue using GTX64389 TIE2 antibody.
Blue : DAPI
Dilution : 1:100

Anti-TIE2 antibody used in IHC (Paraffin sections) (IHC-P). GTX64389

GTX64389 IHC-P Image

IHC-P analysis of rat brain tissue using GTX64389 TIE2 antibody.
Blue : DAPI
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf