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TMEM70 antibody

Anti-TMEM70 antibody used in IHC (Paraffin sections) (IHC-P). GTX85199
Anti-TMEM70 antibody used in Western Blot (WB). GTX85199
Anti-TMEM70 antibody used in IHC (Paraffin sections) (IHC-P). GTX85199

Cat No. GTX85199

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, ELISA

Reactivity

Human, Mouse, Rat
Package
100 μg ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

29 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TMEM70 antibody was raised against a 14 amino acid synthetic peptide near the center of human TMEM70.The immunogen is located within amino acids 150 - 200 of TMEM70.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

transmembrane protein 70 , MC5DN2

Cellular Localization

Mitochondrion inner membrane

Background

TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes. Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer. Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms. It contains a conserved DUF1301 domain and two putative transmembrane regions.

Database

Research Area

DATA IMAGES

Anti-TMEM70 antibody used in IHC (Paraffin sections) (IHC-P). GTX85199

GTX85199 IHC-P Image

IHC-P analysis of rat liver tissue using GTX85199 TMEM70 antibody.
Working concentration : 5 μg/ml

Anti-TMEM70 antibody used in Western Blot (WB). GTX85199

GTX85199 WB Image

WB analysis of human liver tissue lysate using GTX85199 TMEM70 antibody.
Working concentration : 1 μg/ml

Anti-TMEM70 antibody used in IHC (Paraffin sections) (IHC-P). GTX85199

GTX85199 IHC-P Image

IHC-P analysis of rat liver tissue using GTX85199 TMEM70 antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf