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TRPC6 antibody

Anti-TRPC6 antibody used in IHC-P (cell pellet) (IHC-P (cell pellet)). GTX04669
Anti-TRPC6 antibody used in IHC (Paraffin sections) (IHC-P). GTX04669
Anti-TRPC6 antibody used in Western Blot (WB). GTX04669
Anti-TRPC6 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04669

Cat. No. GTX04669

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, ELISA, IHC-P (cell pellet)

Reactivity

 Human, Mouse
Package
100 μg ($429)
See all TRPC6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5-1 μg/mL
ICC/IF 5 μg/mL
IHC-P 10 μg/mL
ELISA Assay dependent
IHC-P (cell pellet) 2 μg/mL
Not tested in other applications.

Calculated MW

106 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

14 amino acid synthetic peptide from near the amino terminus of human TRPC6. The immunogen is located within amino acids 50 - 100 of TRPC6.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transient receptor potential cation channel subfamily C member 6 , FSGS2 , TRP6

Cellular Localization

Cell membrane

Background

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009]

Database

Research Area

DATA IMAGES

Anti-TRPC6 antibody used in IHC-P (cell pellet) (IHC-P (cell pellet)). GTX04669

GTX04669 IHC-P (cell pellet) Image

IHC-P (cell pellet) analysis of K562 cells using GTX04669 TRPC6 antibody.
Dilution : 2 μg/mL

Anti-TRPC6 antibody used in IHC (Paraffin sections) (IHC-P). GTX04669

GTX04669 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX04669 TRPC6 antibody.
Dilution : 10 μg/mL

Anti-TRPC6 antibody used in Western Blot (WB). GTX04669

GTX04669 WB Image

WB analysis of K562 whole cell lysate using GTX04669 TRPC6 antibody.
Lane 1 : 0.5 μg/mL
Lane 2 : 1 μg/mL

Anti-TRPC6 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04669

GTX04669 ICC/IF Image

ICC/IF analysis of K562 cells using GTX04669 TRPC6 antibody.
Red : Primary antibody
Blue : DAPI
Dilution : 5 μg/mL

REFERENCE

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REVIEW

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Package List Price ($)
$ 429