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TSP antibody

Cat No. GTX73136

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IP

Reactivity

Human, Mouse, Bovine
Package
500 μl ($319)

APPLICATION

Application Note

Immunofluorescence; Immunoprecipitation (Native and denatured)(Using Protein A Ab. 10 micrograms/mg protein lysate); Western Blotting (Ab. 5-10 micrograms/ml 2 Hrs. RT)

Calculated MW

38 kDa. ( Note )

Positive Control

HUVEC Cells

PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline, pH 7.2, containing 0.2% BSA & 0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified human platelet TSP

Purification

Protein A affinity purified
From polyclonal serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

thrombopoietin , MGDF , MKCSF , ML , MPLLG , THCYT1 , TPO

Cellular Localization

Secreted

Background

Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014]

Database

Research Area

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf