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TTC5 antibody

Anti-TTC5 antibody used in IHC (Paraffin sections) (IHC-P). GTX85519
Anti-TTC5 antibody used in Western Blot (WB). GTX85519
Anti-TTC5 antibody used in IHC (Paraffin sections) (IHC-P). GTX85519

Cat. No. GTX85519

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all TTC5 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 2 μg/mL
IHC-P 10 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

49 kDa. ( Note )

Positive Control

RAW 264.7 Cell Lysate(GTX27187)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TTC5 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human TTC5.The immunogen is located within the last 50 amino acids of TTC5.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

tetratricopeptide repeat domain 5 , Strap

Cellular Localization

Nucleus,Cytoplasm

Background

Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats (1). Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 (2) and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5 (3), suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.

Database

DATA IMAGES

Anti-TTC5 antibody used in IHC (Paraffin sections) (IHC-P). GTX85519

GTX85519 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX85519 TTC5 antibody.
Working concentration : 10 μg/ml

Anti-TTC5 antibody used in Western Blot (WB). GTX85519

GTX85519 WB Image

WB analysis of RAW264.7 cell lysate using GTX85519 TTC5 antibody.
Working concentration : (A) 0.5, (B) 1, and (C) 2 μg/ml

Anti-TTC5 antibody used in IHC (Paraffin sections) (IHC-P). GTX85519

GTX85519 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX85519 TTC5 antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399