APPLICATION
Application Note
For IHC-P: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.
Calculated MW
Product Note
GTX12359 stains the human neurofibrillary tangles, neuropil threads and neuritic plaques associated with Alzheimer's disease. The antibody also stains astrocytes and ribosomes. Tau 2 may be used with formalin-fixed paraffin-embedded sections of human brain tissue.
PROPERTIES
Form
Liquid
Buffer
PBS pH7.4, 150mM NaCl, 1% BSA
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration
0.1 mg/ml (Please refer to the vial label for the specific concentration.)
Immunogen
Recombinant full length protein.
Purification
Protein A/G purified
Conjugation
Fluorescein isothiocyanate (FITC)
Absorption : 492 nm ; Emission : 518 nm.
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
microtubule associated protein tau , DDPAC , FTDP-17 , MAPTL , MSTD , MTBT1 , MTBT2 , PPND , PPP1R103 , TAU
Cellular Localization
Cytoplasm, cytosol , Cell membrane , Cytoplasm, cytoskeleton , Cytoplasm , Cell projection, dendrite
Background
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]
Database
Research Area
REFERENCE
There are currently no references for Tau antibody [Tau-2] (FITC) (GTX12359). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Tau antibody [Tau-2] (FITC) (GTX12359). Be the first to share your experience with this product.