VEGF Receptor 2 (phospho Tyr1175) antibody

Cat. No. GTX38577

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	IHC-P
Reactivity	Mouse
Package	50 μl ($399)

See all VEGF Receptor 2 products

Datasheet
Document

View product citations for antibody GTX38577 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
IHC-P	Assay dependent

Not tested in other applications.

Calculated MW

152 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.01M TBS, 0.5% BSA, 25% Glycerol

Preservative

0.015% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between KD(p-Y)IV amino acids of human VEGFR2 (phospho-Tyr1175)

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

kinase insert domain receptor , CD309 , FLK1 , VEGFR , VEGFR2

Cellular Localization

Cell junction,Endoplasmic reticulum,Cytoplasm,Nucleus,Cytoplasmic vesicle

Background

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]

Database

Gene ID: 3791 KDR
UniProt: P35968 KDR

Research Area

DATA IMAGES

GTX38577 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX38577 VEGF Receptor 2 (phospho Tyr1175) antibody.
Dilution : 1:200

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Proclin.pdf

Package

List Price ($)

50 μl

$ 399

Qty