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VWF antibody

Anti-VWF antibody used in IHC (Paraffin sections) (IHC-P). GTX26994
Anti-VWF antibody used in IHC (Paraffin sections) (IHC-P). GTX26994
Anti-VWF antibody used in IHC (Paraffin sections) (IHC-P). GTX26994

Cat. No. GTX26994

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($509)
See all VWF products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

309 kDa. ( Note )

Product Note

The antibody specifically reacts with the cytoplasm of human endothelial cells from normal and neoplastic blood and from lymphatic vessels. It also reacts with human endocardium, platelets and megakaryocytes. It may be used for immunohistological studies of the vascular structures in frozen tissue preparations and enzymatically pre-digested, formalin, methacarn, Bouin′s or ethanol-fixed and paraffin-embedded tissue sections.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

von Willebrand Factor (Factor VIII-related antigen) from human plasma.

Purification

IgG fraction

Conjugation

Unconjugated

RRID

AB_369685

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

von Willebrand factor , F8VWF , VWD

Cellular Localization

Secreted

Background

Human von Willebrand factor (factor VIII R:Ag) is a 270kD multimeric plasma glycoprotein. It mediates platelet adhesion to injured vessel walls and serves as a carrier and stabilizer for coagulation factor VIII. The von Willebrand factor has functional binding domains to platelet glycoprotein Ib, glycoprotein IIb/IIIa, collagen and heparin. The factor is synthesized by endothelial cells and is also present in platelets and megakaryocytes.

Database

Research Area

DATA IMAGES

Anti-VWF antibody used in IHC (Paraffin sections) (IHC-P). GTX26994

GTX26994 IHC-P Image

VWF antibody detects VWF protein at cell membrane in mouse liver by immunohistochemical analysis.
Sample: Paraffin-embedded mouse liver.
VWF antibody (GTX26994) diluted at 1:2000.
Anti-VWF antibody used in IHC (Paraffin sections) (IHC-P). GTX26994

GTX26994 IHC-P Image

IHC-P analysis of human kidney tissue using GTX26994 VWF antibody at 1:2,000.

Anti-VWF antibody used in IHC (Paraffin sections) (IHC-P). GTX26994

GTX26994 IHC-P Image

IHC-P analysis of human kidney tissue using GTX26994 VWF antibody at 1:2000.

REFERENCE

Application Reference

Shie MY et al. Materials Science and Engineering: C 2017; 73 : 726-735 Synergistic * in the osteogenic and angiogenic differentiation of human mesenchymal stem cells by calcium silicate–graphene composites.
Application : WB
Crow S et al. Ann Thorac Surg 2010; 90 (4) : 1263-9; discussion 1269 Acquired von Willebrand syndrome in continuous-flow ventricular assist device recipients.
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 509